Timeline: Polio Eradication in the African Region
In the 1900s, polio is one of the most feared childhood diseases in industrialized nations, without a cure.
Regular polio epidemics are happening in North America and Europe.
Polio is thought to only affect industrialized countries and is not considered a ‘tropical disease.’
Yet by 1950, there is growing recognition that polio is also affecting the ‘developing’ world.
1916
A huge polio outbreak in the U.S. paralyses 27,000 and kills 6,000, activating a surge of research.
1918
The first polio epidemic is recognized in South Africa after soldiers return from the Middle East after the First World War.
1929
The ‘iron lung’ – an artificial respirator that helps paralysed polio patients breathe – becomes widely used in Europe and the U.S.
© WHO
1948
South Africa’s largest polio outbreak with 3,000 cases and 200 deaths catalyses a major fundraising campaign. Africa’s first foundation for poliomyelitis research, the Poliomyelitis Research Foundation opens in 1950.
© Poliomyelitis Research Foundation (PRF)
1949-54
Large polio epidemics are seen in Angola, Democratic Republic of Congo (DRC) (then known as Belgian Congo), French Equatorial Africa, Kenya, Zimbabwe (then known as Rhodesia), Uganda and South Africa.
© WHO
By the 1950s, an estimated 600,000 people are paralysed each year around the world.
The development and widespread rollout of the polio vaccine across industrialized countries leads to a steep drop in polio incidence.
Polio cases in Africa are increasing. In 1955, Dr James Gear, director of South Africa’s Poliomyelitis Research Foundation says, “It is clear that the disease is endemic in all the countries of Africa.”
1952-56
Algeria is hit by multiple polio outbreaks related to mass displacement caused by the War of Liberation. The Algiers Hospital of Infectious Diseases establishes a polio service in 1955.
© Prevention Department of Algerian Health Ministry
1953
In Africa, 18 countries report polio cases to the WHO, which sets up a Global Expert Committee on polio and designates a network of WHO regional polio laboratories.
© WHO
1954
Dr Jonas Salk develops the first polio vaccine, an injectable vaccine called the ‘inactivated polio vaccine’ (IPV), which is tested with over one million children in the U.S. in 1955.
© WHO
1956
Dr Albert Sabin develops the oral polio vaccine (OPV), which is used in mass vaccination campaigns in the U.S. in 1961.
© WHO
1957
WHO recommends the use of OPV in field trials during a meeting attended by the world’s top polio specialists.
©WHO
1961-62
24 out of 34 African countries have an increase in polio cases according to WHO and other reports.
© WHO
1962
OPV becomes the ‘vaccine of choice’ for most of the world, because it stops person-to-person transmission, and is easier and less expensive to administer than the injectable vaccine.
© WHO
By the mid-1970s, only a few African countries have immunization activities.
Routine immunization, including the polio vaccine, is introduced globally, but many people are still not reached with the polio vaccine.
1974
168,000 cases of polio are estimated to occur in Africa each year – much higher than originally suspected. This data is based on ‘lameness surveys’ conducted in 14 African countries, starting with Ghana.
© WHO
1976
The Expanded Programme of Immunization (EPI) is established to bring vaccines to the world’s children.
© GPEI
1976
In South Africa, the Poliomyelitis Research Foundation Laboratories open, which later becomes the National Institute for Virology.
© Poliomyelitis Research Foundation (PRF)
1979
The U.S. is officially wild polio-free after extensive nation-wide vaccination campaigns
Success against polio in the U.S. and other developed countries inspires the idea of global polio eradication.
By the late 80s, most African countries are immunizing children against polio as part of routine immunization.
1985
Rotary International launches ‘Polio Plus’, a 20-year commitment to raise funds to protect all children from polio. Rotary chapters around the world begin fundraising.
© Rotary
1988
The World Health Assembly endorses a resolution to eradicate polio worldwide by the year 2000. The ‘Global Polio Eradication Initiative’ (GPEI) is launched – one of the largest public health initiatives in world history.
© WHO
1989
The WHO Regional Committee for Africa adopts the 1988 World Health Assembly resolution and endorses the goal to eradicate polio from the continent.
© WHO
With an estimated 75,000 children paralysed by polio each year, African countries commit to eradicating polio and start implementing eradication strategies in earnest.
The GPEI makes huge investments in training, immunization infrastructure and equipment, disease surveillance, data management and high-level coordination across Africa.
The infrastructure developed to fight polio starts being used to support other disease efforts on the continent.
1996
Organization of African Unity (OAU) leaders adopt the Yaoundé Declaration to eradicate polio in Africa. Nelson Mandela launches the influential ‘Kick Polio out of Africa’ campaign with Rotary International, which is supported by heads of state, African celebrities, football players and philanthropists.
© Courtesy of Rotary International. Permission from Nelson Mandela Foundation
1996
Cameroon, Cote d’Ivoire, Kenya, Tanzania and Uganda conduct the first national immunization days specifically for polio in the African region. By 2000, nearly 30 African countries launch national immunization days.
© Sam Okiror
1998
The Africa Regional Certification Commission (ARCC) for Polio Eradication is appointed to independently oversee certification and containment of polio in all 47 Member State countries.
© ARCC
1998
After large disease outbreaks in West Africa, polio funds and staff are used to scale up surveillance of other communicable diseases, through the Integrated Disease Surveillance Response (IDSR) strategy. Thousands of polio surveillance officers are trained to monitor up to nine other diseases.
© UNICEF
1998
The last wild poliovirus type 2 case is reported in the African region in Nigeria.
1999
The first house-to-house polio campaigns in the African region are conducted in Nigeria, reaching 40% more children than routine immunization, making this an essential strategy for polio eradication.
© WHO
1999
The UN Secretary General Kofi Annan negotiates the first ceasefire agreement between warring parties in DRC to allow ten million children under five years to be immunized against polio over a three month period.
© GPEI
1999
A huge outbreak of polio type 3 occurs in Luanda, Angola after 800,000 displaced people fleeing conflict in DRC seek refuge. A million children under five are vaccinated.
© UNICEF
The number of annual wild poliovirus cases has dropped to under 1,000 worldwide, thanks to mass polio vaccination campaigns.
Almost the whole of eastern and southern Africa stops the transmission of indigenous wild polio. The wild poliovirus is now endemic in just Nigeria and Niger.
There is huge optimism that polio can be eradicated in Africa, but the polio programme faces major challenges. Repeat outbreaks in Nigeria and imported cases in Angola affect other African countries.
24 countries are declared wild polio-free.
2000
The first multi-country synchronized campaigns in western and central Africa take place across 17 countries. Tens of thousands of volunteers vaccinate more than 76 million children.
© UNICEF
2001
The first case of circulating vaccine-derived polio (cVPDV) type 1 is detected in Madagascar, where the last wild polio case was reported in October 1997.
2003
A boycott of the polio vaccine in Northern Nigeria over vaccine safety concerns leads to a polio outbreak that spreads to 20 countries by 2008. In response, Africa mounts a vast multi-country synchronised campaign across 23 countries, reaching 80 million children under five years.
© WHO
2005
An outbreak of wild polio is declared in the Horn of Africa and Yemen, with over 700 cases. Emergency immunization campaigns across eight countries, including Ethiopia and Kenya, reach more than 34 million children.
© UNICEF
2005
Importations of wild polio type 1 from India cause outbreaks in Luanda, Angola with further importations in the country in 2008 and 2009 and cross-border spread to Namibia in 2006. Immunization campaigns are mounted in response.
© Namibia Ministry of Health
2007
After being wild polio-free since 2004, 54 cases of wild poliovirus type 1 are reported across four provinces in DRC.
© UNICEF
2007
In Nigeria, Immunization ‘Plus’ days engage local communities offering ‘add ons’ including other health services and basic goods.
© WHO
2008
The World Health Assembly calls on Nigeria to respond swiftly to a polio outbreak that affects 15 countries in western and central Africa by 2010. Synchronized cross-border vaccination campaigns are conducted across the region. Over 400,000 volunteers and health workers immunize 85 million children.
© Adeniyi-Jones Jidef
2008
When the global economic crisis affects health funding in Africa, polio data management teams fill the gap for malaria and HIV/AIDS data management.
The final march toward certification is marked by huge setbacks as well as the introduction of many innovative strategies and technologies.
A decline in population immunity levels in many African countries puts communities at risk of polio outbreaks.
After being taken off the endemic list in 2015, Nigeria detects new cases in insecure Borno state in 2016. A vast nationwide effort helps Nigeria stamp out the wild poliovirus once and for all.
23 countries are declared wild polio-free.
On 25 August 2020, the WHO African Region becomes the fifth WHO region to have eradicated wild polioviruses.
Despite this incredible public health achievement, the fight against poliovirus is not over.
More than a dozen countries in Africa remain affected by cVDPVs and the GPEI and governments recommit to reaching every child with polio vaccines.
2011
Environmental surveillance for poliovirus is used for the first time in Nigeria and expanded to over 300 sites in 26 countries in the African region.
© Andrew Esiebo/WHO
2012
Nigeria sets up an Emergency Operations Centre and launches a national emergency plan, which propels progress. At this point, Nigeria accounts for 50% of the world’s wild polio cases.
© Bill & Melinda Gates Foundation
2012
The last wild poliovirus of type 3 case is reported in the African region in Nigeria.
2013
After an outbreak of wild poliovirus type 1 in Somalia spreads to Ethiopia and Kenya, large-scale vaccination campaigns are mounted across Horn of Africa countries.
© WHO
2014
The WHO declares wild polio and cVPDVs as a Public Health Emergency of International Concern (PHEIC), spurring an international response.
© UNICEF
2014
Polio infrastructure and technology are used to conduct Ebola case finding and contact tracing in Nigeria.
2015
Wild poliovirus type 2 is declared to have been eradicated globally after the last case in India in 1999.
© GPEI
2016
After almost three years without a case, four cases of wild poliovirus type 1 are detected in northern Nigeria around Lake Chad, following an armed group’s prevention of polio vaccines. A vast multi-country Lake Chad emergency response targets over 45 million children in Nigeria, Niger, Cameroon, Chad and Central African Republic. Nigeria returns to the list of polio endemic countries.
© UN Foundation/Christine McNab
2016
An external review of eight African countries finds that the polio programme has provided major benefits to Africa’s health systems, including for disease surveillance, routine immunization and outbreak response.
© Rotary International
2016
155 countries and territories, including across Africa switch the ‘trivalent’ OPV with the ‘bivalent’ OPV, which does not contain the eradicated type 2 strain.
© WHO/Rotary
2017
The DRC sees a wave of cVDPV outbreaks that leave 29 children paralysed. A national public health emergency is declared.
© UNICEF
2018
There is an increase in reported cVDPV cases across all regions in Africa. Cases are reported in 12 countries with low levels of routine and supplementary vaccination coverage.
© GPEI RRT
2019
The WHO’s Regional Office for Africa sets up a Rapid Response Team to coordinate responses to cVDPV outbreaks.
© GPEI RRT
2019
Nigeria celebrates three years since its last wild polio case, which kickstarts the process for certifying the African region free of wild poliovirus.
© Andrew Esiebo
2020
The WHO African Region is certified to have eradicated wild polio by the ARCC, after passing more than four years without wild polio with certification-standard disease surveillance.